A latex bag tonometer for determining the anaesthetic blood/gas partition coefficient.
نویسندگان
چکیده
Many techniques for measurement of the tissue/gas partition coefficient are valid. Each has specific advantages and shortcomings. All the methods require suitable analytic equipment and means for controlling temperature. The disadvantages of a particular technique, the ability to cope with them and the availability of the necessary apparatus are the determining factors in choosing the best method. The latex bag tonometer has a precision and ease which compares favourably with previously described techniques for measuring anaesthetic blood/gas partition coefficients. The technique was successfully used to show the effect of in vivo haemodilution on the halothane blood/gas partition coefficient.
منابع مشابه
Determination of the partial pressure of halothane (or isoflurane) in blood.
A gas chromatographic method is described for the direct quantitative determination of the partial pressure of halothane (or isoflurane) in blood as well as the blood-gas partition coefficient. A head space technique and a flame ionization detector were used. Standard blood was obtained by equilibrating patients' blood with known gas concentrations in a tonometer. Using an infra-red analyser to...
متن کاملSolubility of nitrous oxide in human blood.
The solubility of nitrous oxide in blood at body temperature was determined by Siebeck (1) with considerable accuracy as early as 1909. In his experiment, the blood was placed with a gas mixture in a tonometer of 3 liters capacity and equilibrated at 38” and atmospheric pressure. After an equilibrium had been attained, samples of both blood and gas were analyzed for nitrous oxide content. A blo...
متن کاملAlcohol increases the solubility of anaesthetics in the liver.
Liver/gas partition coefficients for isoflurane, enflurane, halothane and methoxyflurane increased two-fold in rats killed 16 h after a single injection of 15% ethanol 7 g kg-1. In contrast, blood/gas and brain/gas partition coefficients did not change. Chronic (21 days) ingestion of ethanol increased liver/gas partition coefficients four-fold, although this increase was largely attributable to...
متن کاملAnaesthetic uptake and elimination: is there a difference between halothane and isoflurane in the dog?
In two groups of dogs, the uptake and elimination of halothane and isoflurane were studied using a closed-loop anaesthetic system which automatically controlled end-tidal halothane and isoflurane partial pressures at equi-MAC concentrations. Haemodynamic and respiratory variables were recorded and the anaesthetic partial pressures were measured in the inspired and expired air, as well as in the...
متن کاملSolubility characteristics of the ideal agent for measurement of cardiac output by soluble gas uptake methods.
Measurements of the rate of uptake of soluble gases such as nitrous oxide or acetylene has been used as the basis of a method of cardiac output estimation since 1912. Using theoretical models of single, multiple and rebreathing techniques of cardiac output measurement, we determined the effect of solubility in blood and lung tissue on the changes in the final expired concentration of the gas. D...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Canadian Anaesthetists' Society journal
دوره 23 5 شماره
صفحات -
تاریخ انتشار 1976